
Discover how the integumentary system works



The integumentary system plays a vital role in your body’s overall health and well-being. As the most visible system, it forms the protective barrier of skin, hair, nails, and glands that shields you from the external environment. More than just a physical covering, the integumentary system is a dynamic, multifunctional organ system. This bodily system is responsible for providing essential protection, regulating body temperature, and enabling sensation.
Understanding the function of the integumentary system helps highlight its importance in daily life and is essential knowledge for medical board exams like the National Physical Therapy Examination (NPTE). Let’s explore this remarkable system in greater detail and its importance in patient and personal care.

What is the integumentary system?
This part of your body includes your largest organ and the one that takes on the most battles. Your skin weighs around six pounds and is two millimeters thick, wrapping around your entire body.
It also includes what is on your skin, like your hair, nails, and exocrine glands. Your exocrine glands produce and release sweat (eccrine and apocrine), oil (sebaceous), earwax (ceruminous), and milk (mammary). These glands are essential for helping release excess toxins from the body.
The skin
Now let’s take a deeper dive into the layers of your skin.
The epidermis is the top waterproof barrier. It contains keratinocytes, melanocytes (pigment), Langerhans (immune), and other specialized cells. The epidermis helps shield the body against germs, the sun, injury, and other disruptors. It regenerates about every 30 days.
Next up is the dermis. This thick middle layer of skin is packed with collagen, which is the elastin necessary for strength and flexibility. The dermis contains many blood vessels that regulate nutrition, temperature control, nerves, hair follicles, oil, and sweat glands. The third layer is the hypodermis, which is also considered the subcutaneous layer. The hypodermis consists of fatty tissue that cushions the muscles and bones. It also insulates and connects the skin to its deeper layers.
Hair, skin, and glands
Your hair grows from thousands of follicles located in the dermis. Hair helps to conserve heat, shield your skin from UV light, and gives sensory feedback like goosebumps from the arrector pili.
Nails are found on the phalanges, or fingers and toes. They are comprised of hard keratin to protect. The nail plate, bed, cuticle, growth matrix, and lunula visible under the base are all considered part of the integumentary system.
Your glands include the sweat glands, which regulate temperature and excrete waste. Sebaceous glands produce sebum to moisturize and protect your skin. The ceruminous (earwax) and mammary glands are also included.
Core functions of the integumentary system
The integumentary system plays several vital roles in maintaining overall health. One primary function of the integumentary system is to serve as a protective barrier against environmental hazards such as pathogens, physical injuries, and harmful UV radiation. The skin’s unique pH level, along with its acidic secretions, helps deter the growth of germs and significantly reduces the risk of infections.
Thermoregulation represents another core function, where sweat production and blood vessel adjustments help regulate and maintain stable body temperature. These thermoregulatory responses of the integumentary system ensure that heat is dissipated or retained as needed to keep you comfortable and protected.
Sensation is an additional essential function of the integumentary system. Through diverse nerve endings, the skin detects stimuli such as touch, pressure, pain, and temperature. This sensory capability provides crucial information about surroundings and potential harm.
The integumentary system also participates in excretion; sweat glands remove waste products like salts and urea through perspiration, supporting bodily detoxification. Sebum produced by sebaceous glands lubricates the surface while preserving essential moisture, contributing further to skin health.
A key metabolic function of the integumentary system includes the synthesis and storage of important nutrients. Producing vitamin D in response to UV exposure is one example that is critical for bone health and proper calcium metabolism. Additionally, the integumentary system stores important reserves of fat, water, and glucose. These structures benefit immune responses, as seen with Langerhans cells that patrol for harmful invaders within the skin.
The integumentary system plays a comprehensive role in protection, temperature regulation, sensation, waste excretion, nutrient synthesis, and immune support, making it an indispensable part of human physiology.

Interactions with other body systems
- The immune system: A strong immune system serves as the body’s first barrier, triggering healing and defense against threats.
- The circulatory system: Blood vessel action controls heat loss and retention, key for rehabilitation and overall health.
- The skeletal and digestive tract: Vitamin D supports calcium absorption, which promotes bone health and strength.
- The nervous system: Physical therapists and other healthcare professionals must learn how sensory nerves relay environmental stimuli to assess patient needs.
- The respiratory system: Nose hairs help filter air, contributing to respiratory health and optimal patient outcomes.
The integumentary system in physical therapy
Knowing how the integumentary system functions and how certain conditions manifest through the skin and nervous system is a key aspect of physical therapy. The skin is one of the most sensitive parts of the body, and physical therapy professionals must be aware of how manipulative therapy affects the skin to ensure the most comfortable experience for the patient. Clinicians, assistants, and aides must be ready to efficiently and effectively treat cuts, scrapes, and bruises in the event of injury or accident during therapy. Maintaining a sanitized, safe physical therapy center prevents further damage or illness in the event of skin abrasions.
Anyone working in a physical therapy clinic should be able to identify issues related to the integumentary system, have expertise in its core functions, and take steps to avoid epidermal injury. The integumentary system is covered on both the NPTE-PT (for physical therapists) and NPTE-PTA (for physical therapist assistants), highlighting its importance in physical therapy jobs. While physical therapy focuses mainly on other systems of the body, such as the musculoskeletal and neuromuscular systems, integumentary care is a significant part of physical therapy education.
How to keep your integumentary system healthy
You don’t need to be in the medical field to know that skin protection is important, and protecting your integumentary system consistently is the best way to keep it healthy. Dermatologists strongly recommend using a broad-spectrum SPF 30+ sunscreen daily to shield your skin from harmful UV rays. Cleanse gently with mild cleansers, then moisturize to support the skin’s natural barrier.
Staying hydrated is crucial; drink plenty of water, particularly after exercise or if you perspire frequently at a physical therapy clinic. Avoid tanning beds, as they can severely damage the skin barrier. Manage your stress levels and stop smoking to enhance your integumentary and overall systemic health. Regularly monitor moles or skin changes.
If you notice persistent or concerning skin issues, seek medical attention and consult a dermatologist promptly. Knowing how to spot skin concerns is a crucial part of any medical specialist, especially those working in close contact with patients. Maintaining vigilant skin care practices is fundamental for students, clinicians, and anyone interested in optimal healing and recovery.

Conclusion
The integumentary system is a powerhouse and a multipurpose tool. Its function extends far beyond appearance; it acts as a barrier, sensor, regulator, and healer, all of which are highlighted in the NPTE content outline. This remarkable system connects you to your environment, defends against external threats, and ensures your body’s internal balance. Protect it and your patients daily; our skin, hair, nails, and glands carry us through life with resilience and vitality.

